下面简单阅读示例：

using NPOI.HSSF.UserModel;
using NPOI.SS.UserModel;

//.....

private void button1_Click(object sender, EventArgs e)
{
    HSSFWorkbook hssfwb;
    using (FileStream file = new FileStream(@"c:\test.xls", FileMode.Open, FileAccess.Read))
    {
        hssfwb= new HSSFWorkbook(file);
    }

    ISheet sheet = hssfwb.GetSheet("Arkusz1");
    for (int row = 0; row <= sheet.LastRowNum; row++)
    {
        if (sheet.GetRow(row) != null) //null is when the row only contains empty cells 
        {
            MessageBox.Show(string.Format("Row {0} = {1}", row, sheet.GetRow(row).GetCell(0).StringCellValue));
        }
    }
}

顺便说一句：在NPOI网站这里在下载部分有例子包-
的C＃示例一包。如果尚未尝试，请尝试一下。:)