警告：此答案适用于Scrapy v0.7，自那时以来，spider管理器api发生了很大变化。

覆盖默认的SpiderManager类，从数据库或其他地方加载自定义规则，并使用自己的规则/正则表达式和domain_name实例化自定义spider

在mybot / settings.py中：

SPIDER_MANAGER_CLASS = 'mybot.spidermanager.MySpiderManager'

在mybot / spidermanager.py中：

from mybot.spider import MyParametrizedSpider

class MySpiderManager(object):
    loaded = True

    def fromdomain(self, name):
        start_urls, extra_domain_names, regexes = self._get_spider_info(name)
        return MyParametrizedSpider(name, start_urls, extra_domain_names, regexes)

    def close_spider(self, spider):
        # Put here code you want to run before spiders is closed
        pass

    def _get_spider_info(self, name):
        # query your backend (maybe a sqldb) using `name` as primary key, 
        # and return start_urls, extra_domains and regexes
        ...
        return (start_urls, extra_domains, regexes)

现在是您的自定义spider class，位于mybot / spider.py中：

from scrapy.spider import BaseSpider

class MyParametrizedSpider(BaseSpider):

    def __init__(self, name, start_urls, extra_domain_names, regexes):
        self.domain_name = name
        self.start_urls = start_urls
        self.extra_domain_names = extra_domain_names
        self.regexes = regexes

     def parse(self, response):
         ...