我假设您正在使用py2exe生成exe。您需要在setup.py文件中指定Selenium Webdriver的位置。

以下代码应有所帮助：

from distutils.core import setup
import py2exe

# Change the path in the following line for webdriver.xpi
data_files = [('selenium/webdriver/firefox', ['D:/Python27/Lib/site-packages/selenium/webdriver/firefox/webdriver.xpi'])]

setup(
    name='General name of app',
    version='1.0',
    description='General description of app',
    author='author name',
    author_email='author email',
    url='',
    windows=[{'script': 'abc.py'}],   # the main py file
    data_files=data_files,
    options={
        'py2exe':
            {
                'skip_archive': True,
                'optimize': 2,
            }
    }
)