您可以通过两种方式设置from参数：

var SendGrid = require('sendgrid').SendGrid;
var sendgrid = new SendGrid(user, key);
sendgrid.send({
  to: 'you@yourdomain.com',
  from: 'example@example.com',  // Note that we set the `from` parameter here
  fromname: 'Name', // We set the `fromname` parameter here
  subject: 'Hello World',
  text: 'My first email through SendGrid'
}, function(success, message) {
  if (!success) {
    console.log(message);
  }
});

或者您可以创建一个Email对象并在其上填写以下内容：

var Email = require('sendgrid').Email;
var email = new Email({
  to: 'you@yourdomain.com',
  from: 'example@example.com',
  fromname: 'Name',
  subject: 'What was Wenger thinking sending Walcott on that early?',
  text: 'Did you see that ludicrous display last night?'
});

sendgrid.send(email, function() { 
  // ... 
});

您可能需要花几分钟时间浏览Github页面上的README文档。它具有有关如何使用该库及其提供的各种功能的非常详细的信息。