我已经做到了，并且还通过以下方式大量定制了Json.NET正在执行的序列化：

替换global.asax.cs中的默认格式化程序Application_Start：

GlobalConfiguration.Configuration.Formatters.Remove(GlobalConfiguration.Configuration.Formatters.JsonFormatter);
GlobalConfiguration.Configuration.Formatters.Add(new CustomJsonMediaTypeFormatter());

我的CustomJsonMediaTypeFormatter是：

public static class CustomJsonSettings
{
    private static JsonSerializerSettings _settings;

    public static JsonSerializerSettings Instance
    {
        get
        {
            if (_settings == null)
            {
                var settings = new JsonSerializerSettings();

                // Must convert times coming from the client (always in UTC) to local - need both these parts:
                settings.Converters.Add(new IsoDateTimeConverter { DateTimeStyles = System.Globalization.DateTimeStyles.AssumeUniversal }); // Critical part 1
                settings.DateTimeZoneHandling = DateTimeZoneHandling.Local;   // Critical part 2

                // Skip circular references
                settings.ReferenceLoopHandling = ReferenceLoopHandling.Ignore;

                // Handle special cases in json (self-referencing loops, etc)
                settings.ContractResolver = new CustomJsonResolver();

                _settings = settings;
            }

            return _settings;
        }
    }
}

public class CustomJsonMediaTypeFormatter : MediaTypeFormatter
{
    public JsonSerializerSettings _jsonSerializerSettings;

    public CustomJsonMediaTypeFormatter()
    {
        _jsonSerializerSettings = CustomJsonSettings.Instance;

        // Fill out the mediatype and encoding we support
        SupportedMediaTypes.Add(new MediaTypeHeaderValue("application/json"));
        SupportedEncodings.Add(new UTF8Encoding(false, true));
    }

    public override bool CanReadType(Type type)
    {
        return true;
    }

    public override bool CanWriteType(Type type)
    {
        return true;
    }

    public override Task<object> ReadFromStreamAsync(Type type, Stream stream, HttpContent content, IFormatterLogger formatterLogger)
    {
        // Create a serializer
        JsonSerializer serializer = JsonSerializer.Create(_jsonSerializerSettings);

        // Create task reading the content
        return Task.Factory.StartNew(() =>
        {
            using (StreamReader streamReader = new StreamReader(stream, SupportedEncodings.First()))
            {
                using (JsonTextReader jsonTextReader = new JsonTextReader(streamReader))
                {
                    return serializer.Deserialize(jsonTextReader, type);
                }
            }
        });
    }

    public override Task WriteToStreamAsync(Type type, object value, Stream stream, HttpContent content, TransportContext transportContext)
    {
        // Create a serializer
        JsonSerializer serializer = JsonSerializer.Create(_jsonSerializerSettings);

        // Create task writing the serialized content
        return Task.Factory.StartNew(() =>
        {
            using (StreamWriter streamWriter = new StreamWriter(stream, SupportedEncodings.First()))
            {
                using (JsonTextWriter jsonTextWriter = new JsonTextWriter(streamWriter))
                {
                    serializer.Serialize(jsonTextWriter, value);
                }
            }
        });
    }
}

最后，CustomJsonResolver：

public class CustomJsonResolver : DefaultContractResolver
{
    protected override IList<JsonProperty> CreateProperties(Type type, Newtonsoft.Json.MemberSerialization memberSerialization)
    {
        var list = base.CreateProperties(type, memberSerialization);

        // Custom stuff for my app
        if (type == typeof(Foo))
        {
            RemoveProperty(list, "Bar");
            RemoveProperty(list, "Bar2");
        }

        return list;
    }

    private void RemoveProperty(IList<JsonProperty> list, string propertyName)
    {
        var rmc = list.FirstOrDefault(x => x.PropertyName == propertyName);

        if (rmc != null)
        {
            list.Remove(rmc);
        }
    }
}